Vijay Ramalingam
Previous Experience and Education:
Visiting Assistant Professor, Union College, Schenectady, NY, 2015-2018.
Postdoctoral Fellow, Columbia University, New York, NY, 2012-2015.
Postdoctoral Fellow, Trinity University, San Antonio, TX , 2009-2012.
Ph.D. in Organic Chemistry, The Graduate Center, CUNY, NY, 2004-2009.
Senior Chemist, Dr Reddy's laboratories, Hyderabad, India, 2001-2004.
M.Sc. in Applied Chemistry, Anna University, Chennai, India, 1999-2001.
Research Interest:
- Our primary objective is to spearhead the advancement of a pioneering methodology concerning Mechanically Interlocked Molecules (MIMs), encompassing structures such as rotaxanes and catenanes, within the realm of supramolecular chemistry. Central to our endeavor is the development of a robust technique aimed at augmenting the properties of late stage drug molecules through the strategic application of this innovative approach.
- Project 2 involves a collaborative effort with Professor Mahesh Pattabiraman from the University of Nebraska at Kearney. Our joint focus is on utilizing supramolecular assistance to precisely control the generation of single oxygen, a crucial component in various chemical and biological processes. Singlet oxygen refers to a highly reactive form of molecular oxygen (O 2 ) that exists in an excited electronic state with two unpaired electrons in separate spin orbitals. Singlet oxygen is known for its ability to participate in oxidation reactions and is often involved in processes related to photodynamic therapy and the degradation of organic pollutants in the environment.
Selected Publications: ( * publication from SUNY Poly)
- Regmi S, Maharjan A, Ramalingam V, Ramasamy E, Pattabiraman M. Supramolecular Enhancement of BODIPY Singlet Oxygen Generation Using Bile Salt Micelles. * Austin J Anal Pharm Chem. 2023; 10(2): 1161.
- Unravelling supramolecular photocycloaddition: Cavitand-mediated reactivity of 3-(Aryl) Acrylic acids.A Kashyap, V Balraj, V Ramalingam, M Pattabiraman *Journal of Photochemistry and Photobiology A: Chemistry 425, 113695, 2022.
- Supramolecular control of singlet oxygen generation A.Kashyap, E. Ramasamy, V. Ramalingam and M. Pattabiraman, *Molecules, 2021, 26, 2673.
- Magnesium pyrophosphates in enzyme mimics of nucleotide synthases and kinases and in their prebiotic chemistry P Gopinath, V Ramalingam, R Breslow Proceedings of the National Academy of Sciences 112 (39), 12011-12014, 2015
- Chloride sensing via suppression of excited state intramolecular proton transfer in squaramides M Porel, V Ramalingam, ME Domaradzki, VG Young, V Ramamurthy, ... Chemical Communications 49 (16), 1633-1635, 2013
- Cucurbit [8] uril rotaxanes V Ramalingam, AR Urbach Organic Letters 13 (18), 4898-4901, 2011
- Nanomolar binding of peptides containing noncanonical amino acids by a synthetic receptor LA Logsdon, CL Schardon, V Ramalingam, SK Kwee, AR Urbach Journal of the American Chemical Society 133 (42), 17087-17092, 2011
SUNY Polytechnic Undergraduate Research Students:
- Alexander Brink(2022-24)
- Aiyana Miles (2023-24)
- Ajdin Vukovic (2023-24)
- Eh Thaw (2022-23)
- Ohmida Dahab (2022-23)
- Dinah Bell (2022-23)
- Htoo Shee (2022-23)
- Ayuong Arop (2020-21)
- Maja Bajic (2019-20)
List of Instruments:
- UV-Vis Spectrometer
- FTIR
- 1H, 13C, 19F NMR
- Microwave Reactor
- GC-MS
- Isothermal calorimetry (ITC)
- Dyanamic light scattering (DLS)
- High Performance Liquid chromatograph
- Buchi rota vapor