SUNY Poly President Dr. Winston Soboyejo and peers recently published a research paper in Scientific Reports titled, “In-vivo studies of targeted and localized cancer drug release from microporous poly-di-methyl-siloxane (PDMS) devices for the treatment of triple negative breast cancer.” Their paper is significant because it presents a new way to treat triple negative breast cancer, which is a very challenging disease, and possibly prevent triple-negative cancer reoccurrence.  

President Soboyejo led an interdisciplinary research team in the development of a novel implantable device that locally releases targeted cancer drugs that attach specifically to Luteinizing Hormone Releasing Hormone (LHRH) receptors that are over-expressed on the surfaces of triple negative breast cancer cells/tissues, following tumor resection/removal, and the controlled delivery of such drugs for durations that are relevant to chemotherapy. The extended release and delivery of the localized targeted drugs is shown to decrease possible toxicity effects, while preventing breast tumor xenograft recurrence, following the localized, extended release of the targeted cancer drugs in animal experiments.  

To view the published paper, click here.