SUNY Poly’s Dr. Vijay Ramalingam publishes collaborative chemistry research which could improve natural product drugs synthesis

SUNY Poly’s Dr. Vijay Ramalingam publishes collaborative chemistry research which could improve natural product drugs synthesis

Published:
Thursday, December 9, 2021 - 11:44
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Many natural product drugs, such as Piperarborenine B (anticancer), incarvillateine (pain killing), and pauferrol A (topoisomerase II inhibitory activity) contain cyclobutane moiety with a specific stereochemistry.

The paper, “Unravelling supramolecular photocycloaddition: Cavitand-mediated reactivity of 3-(Aryl)Acrylic acids,” published in the Journal of Photochemistry and Photobiology A: Chemistry by SUNY Poly Assistant Professor of Biology Dr. Vijay Ramalingam, with researchers from the University of Nebraska at Kearney, helps to achieve these cyclobutane rings with a precise stereochemistry using the supramolecular photo-cycloaddition reactions (PCA).

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