Talks at Recent Conferences
Transplantable neural circuitry for spinal cord injury. Society for Neuroscience. Chicago. October 2019
Manipulating Kinesin-Tubulin-MTOC Interactions For Engineering Polarized Networks. Biophysical Society. Vancouver, Canada, June 2017.
International Conference on Stem Cell Engineering, San Francisco, October 2016.
Precision Medicine in Oncology. SUNY Academic Industry Roundtable. Panelist and Speaker. 2016
Pluripotency and Ethnic Diversity in Neural and Cardiac Stem Cell Tissue Engineering. Emerging Scholar Spotlight.
Task Force on Minorities Aging and Health Disparities Research, NIH NIA. May 2015
Decoding Neuron-Glia Microarchitectures by Stem Cell Nanotechnology. Bioengineering and Stem Cell Research, RPI, June 2015.
Biological platforms in self-assembly and dynamic restructuring. Workshop 14w5170: Biological and Bio-Inspired Information Theory. Banff International Research Station for Mathematical Innovation and Discovery (BIRS), Canada, October 2014.
Select Recent Publications
Z.T. Olmsted and J.L. Paluh (2021) A gastruloid model for intrinsic nervous integration of the human heart. In preparation.
S. Chandra, J.L. Paluh, R. Chatterjee, A. Mukherjee and S. Pal (2021) A dynamic nanoscale axonal microtubule organization, DyNAMO, model reveals interplay of kinesin with staggered microtubule bundles along the axon length. In preparation.
Z.T. Olmsted, C. Stigliano, B. Marzullo, A. Scimemi, J. Cibelli, P. Horner, and J.L. Paluh (2020) Fully characterized mature human iPS- and NMP- derived motor neurons thrive without neuroprotection in the spinal contusion cavity. Frontiers Cellular Neuroscience. In revision.
Rounak, Paluh, Mukherjee (2021) SyNC, a computationally extensive and realistic neural net to identify relative impacts of synaptopathy mechanisms on glutamatergic neurons and their networks in Autism and complex neurological disorders. Frontiers in Cellular Neuroscience. 15:674030. doi: 10.3389/fncel.2021.674030
Rounak, Paluh, Mukherjee (2021) Pre-SYNC: Hardware realization of the pre-synaptic region of a biologically extensive neural circuitry. 34th International Conference on VLSI Design & 20th International Conference on Embedded Systems.
Z.T. Olmsted, C. Stigliano, A. Scimemi, T. Wolfe, J. Cibelli, P.J. Horner, and J.L. Paluh (2021) Transplantable human motor networks as a neuron-directed strategy for spinal cord injury. iScience. 24:102827. doi: 10.1016/j.isci.2021.102827
Z.T. Olmsted and J.L. Paluh (2021) Stem cell neurodevelopmental solutions for restorative treatments of the human trunk and spine. Frontiers in Cellular Neuroscience. 15:667590. doi: 10.3389/fncel.2021.667590
Z.T. Olmsted and J.L. Paluh (2021) Co-development of central and peripheral neurons with trunk mesendoderm in human elongating multi-lineage organized gastruloids. Nature Communications 12:3020. doi: 10.1038/s41467-021-23294-7
Z.T. Olmsted, C. Stigliano, A. Badri, F. Zhang, A. Williams, M.A.G. Koffas, Y. Xie, R. Linhardt, J. Cibelli, P. Horner and J.L. Paluh (2020) Fabrication of homotypic neural ribbons as a multiplex platform optimized for spinal cord delivery. Scientific Reports. 10:12939. doi: 10.1038/s41598-020-69274-7
M.A.A. Abdullah, N. Amini, L. Yang, J.L. Paluh and J. Wang (2020) Multiplexed analysis of neural cytokines signaling by a novel neural cell-cell interaction microchip. Lab Chip. 20:3980-3995. doi: 10.1039/d0lc00401d
N. Amini, J.L. Paluh, Y. Xie, V. Saxena, and S.T. Sharfstein (2020) Insulin production from hiPSC-derived pancreatic cells in a novel wicking matrix bioreactor. Biotechnology and Bioengineering. doi.org/10.1002/bit.27359
M.L. Tomov, Olmsted Z.T., H. Dogan, E. Gongonrurler, M. Tsompana, H.H. Out, M. Buck, E-A. Chang, J. Cibelli, and J.L. Paluh (2016) Distinct and shared determinants of cardiomyocyte contractility in multi-lineage competent and ethnically diverse iPSCs. Scientific Reports, 6:37637. doi: 10.1038/srep37637
J. Wang, B. Egnot, J.L. Paluh (2016) Cell competition and cooperation in tissue development. J Tissue Sci Eng. 7:2 doi: 10.4172/2157-7552.1000131
M.L. Tomov, M. Tsompana, Z.T. Olmsted, M. Buck, and J.L. Paluh (2016) Human embryoid body transcriptomes reveal maturation differences influenced by size and formation in custom microarrays. J Nanosci and Nanotech, Special Issue Role of Nanotechnology in Stem Cell Research.16:8978-8988.
E-A Chang, M. Tomov, S.T. Suhr, J. Luo, Z.T. Olmsted, J.L. Paluh and J. Cibelli (2015) Derivation of Ethnically Diverse Human Induced Pluripotent Stem Cell Lines. Scientific Reports 5:15234. doi: 10.1038/srep15234
Z.T. Olmsted, A. Colliver, T.D. Riehlman, and J.L. Paluh (2014) Kinesin-14 and kinesin-5 antagonistically regulate microtubule nucleation -TuRC in yeast and human cells. Nature Communications 5:5339. doi:10.1038/ncomms6339.
Mathematical Modeling/Computational Neuroscience/Neuromorphic Hardware
A. Banerjee, J.L. Paluh, et al. (2018). Modeling the neuron as a nanocommunication system to identify spatiotemporal molecular events in neurodegenerative disease. Int J Nanomedicine, 13:3105-3128. doi: 10.2147/IJN.S152664
IEEE Standards Association
S.F. Bush, J.L. Paluh, G. Piro, V. Rao, V. Prasad, and A. Eckford (2015) Defining Communication at the Bottom. IEEE Journal series on Selected Areas of Communication (JSAC): Molecular, Biological and Multi-Scale Communications.
S.F. Bush, J.L. Paluh, G. Piro, V. Rao, V. Prasad, A. Eckford, et al. (2015) P1906.1TM-2015 Recommended Practice for Nanoscale and Molecular Communication Framework. IEEE SA Active Standard. ISBN: 978-1-5044-01-1-2
T.D. Riehlman, Z.T. Olmsted, and J.L. Paluh (2012) Molecular Motors, Chapter 4 in The Nanobiotechnology Handbook, CRC Press/Taylor and Francis Group. ISBN: 9781439838693.
B. Riggs, J.L. Paluh, G. Plopper, and D.B. Chrisey (2011) Impedance Spectroscopy for Characterization of Biological Function, Chapter 12 in NanoCellBiology: Multimodal Imaging In Biology and Medicine, Pan Sanford Publishing Pte. Ltd. ISBN: 9789814411790 doi: 10.4032/9789814411806
Patents and Disclosures
“MTOC-Inactivating Peptide” J.L. Paluh and Z.T. Olmsted (2017) PATENT: 9,567,380, New Kinesin-5 mechanism and inactivation improves anti-mitotic efficacy over current Kinesin-5 drugs.
“MTOC-Inactivating Peptide”. J.L. Paluh and Z.T. Olmsted. Provisional Patent: 61/939.461, February 2014. Novel peptide agents that block spindle formation by targeted inactivation of the -TuRC microtubule organizing center.
“Combined devices for use in high content retention, tracking, and 3D-multi-cellular aggregate patterning and analysis”. J.L. Paluh, M. Tomov, and T. Riehlman. SUNY Poly CNSE Invention Disclosure, May 2014. Stem cell niche manipulating platforms.